Item Type | Name |
Academic Article
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Patterns of gene expression in different histotypes of epithelial ovarian cancer correlate with those in normal fallopian tube, endometrium, and colon.
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Academic Article
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Exploratory analysis of the copy number alterations in glioblastoma multiforme.
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Academic Article
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Proteomic and transcriptomic profiling reveals a link between the PI3K pathway and lower estrogen-receptor (ER) levels and activity in ER+ breast cancer.
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Concept
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Gene Expression Profiling
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Academic Article
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Comprehensive molecular characterization of clear cell renal cell carcinoma.
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Academic Article
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The Cancer Genome Atlas Pan-Cancer analysis project.
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Academic Article
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The somatic genomic landscape of glioblastoma.
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Academic Article
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A network-based, integrative study to identify core biological pathways that drive breast cancer clinical subtypes.
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Academic Article
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Integrated genomic analyses of ovarian carcinoma.
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Academic Article
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Molecular characterization of gallbladder cancer using somatic mutation profiling.
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Academic Article
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Genome-wide transcriptome profiling of homologous recombination DNA repair.
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Academic Article
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Ischemia in tumors induces early and sustained phosphorylation changes in stress kinase pathways but does not affect global protein levels.
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Academic Article
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Comprehensive genomic analysis identifies novel subtypes and targets of triple-negative breast cancer.
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Academic Article
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Cupid: simultaneous reconstruction of microRNA-target and ceRNA networks.
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Academic Article
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Integrative analysis of cyclin protein levels identifies cyclin b1 as a classifier and predictor of outcomes in breast cancer.
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Academic Article
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Gene and protein expression markers of response to combined antiangiogenic and epidermal growth factor targeted therapy in renal cell carcinoma.
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Academic Article
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Mammalian target of rapamycin activator RHEB is frequently overexpressed in human carcinomas and is critical and sufficient for skin epithelial carcinogenesis.
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Academic Article
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Profiling of residual breast cancers after neoadjuvant chemotherapy identifies DUSP4 deficiency as a mechanism of drug resistance.
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Academic Article
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Modeling precision treatment of breast cancer.
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Academic Article
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Clinical significance of CTNNB1 mutation and Wnt pathway activation in endometrioid endometrial carcinoma.
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Academic Article
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Genetic analysis of early- versus late-stage ovarian tumors.
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Academic Article
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Overexpression of kallikrein 10 in epithelial ovarian carcinomas.
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Academic Article
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Molecular therapeutics: promise and challenges.
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Academic Article
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Stem cell-ness: a "magic marker" for cancer.
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Academic Article
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Bayesian models based on test statistics for multiple hypothesis testing problems.
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Academic Article
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Astrocytes upregulate survival genes in tumor cells and induce protection from chemotherapy.
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Academic Article
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HDAC4-regulated STAT1 activation mediates platinum resistance in ovarian cancer.
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Academic Article
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Gene expression signature analysis identifies vorinostat as a candidate therapy for gastric cancer.
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Academic Article
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Activation of YAP1 is associated with poor prognosis and response to taxanes in ovarian cancer.
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Academic Article
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Future for ovarian cancer screening: novel markers from emerging technologies of transcriptional profiling and proteomics.
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Academic Article
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A genetically defined model for human ovarian cancer.
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Academic Article
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Amplification of PVT1 contributes to the pathophysiology of ovarian and breast cancer.
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Academic Article
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A functional genetic approach identifies the PI3K pathway as a major determinant of trastuzumab resistance in breast cancer.
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Academic Article
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A systems approach to analysis of molecular complexity in breast cancer.
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Academic Article
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Characterization of a naturally occurring breast cancer subset enriched in epithelial-to-mesenchymal transition and stem cell characteristics.
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Academic Article
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PIK3CA mutations associated with gene signature of low mTORC1 signaling and better outcomes in estrogen receptor-positive breast cancer.
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Academic Article
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Personalizing therapy for ovarian cancer: BRCAness and beyond.
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Academic Article
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A gene expression signature from human breast cancer cells with acquired hormone independence identifies MYC as a mediator of antiestrogen resistance.
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Academic Article
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Two phases of mitogenic signaling unveil roles for p53 and EGR1 in elimination of inconsistent growth signals.
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Academic Article
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Modeling ductal carcinoma in situ: a HER2-Notch3 collaboration enables luminal filling.
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Academic Article
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EGR1 and the ERK-ERF axis drive mammary cell migration in response to EGF.
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Academic Article
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Gene expression, molecular class changes, and pathway analysis after neoadjuvant systemic therapy for breast cancer.
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Academic Article
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An epithelial-mesenchymal transition gene signature predicts resistance to EGFR and PI3K inhibitors and identifies Axl as a therapeutic target for overcoming EGFR inhibitor resistance.
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Academic Article
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Inferring tumour purity and stromal and immune cell admixture from expression data.
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Academic Article
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Non-parametric quantification of protein lysate arrays.
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Academic Article
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Trastuzumab has preferential activity against breast cancers driven by HER2 homodimers.
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Academic Article
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Systematic analysis of genotype-specific drug responses in cancer.
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Academic Article
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AKT-independent signaling downstream of oncogenic PIK3CA mutations in human cancer.
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Academic Article
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Influence of DNA copy number and mRNA levels on the expression of breast cancer related proteins.
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Academic Article
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Elafin drives poor outcome in high-grade serous ovarian cancers and basal-like breast tumors.
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Academic Article
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Concordance of genomic alterations between primary and recurrent breast cancer.
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Academic Article
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PIK3CA mutations in androgen receptor-positive triple negative breast cancer confer sensitivity to the combination of PI3K and androgen receptor inhibitors.
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Academic Article
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Molecular profiling of endometrial carcinoma precursor, primary and metastatic lesions suggests different targets for treatment in obese compared to non-obese patients.
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Academic Article
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Co-clinical assessment identifies patterns of BRAF inhibitor resistance in melanoma.
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Academic Article
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A decision support framework for genomically informed investigational cancer therapy.
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Academic Article
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Co-occurring genomic alterations define major subsets of KRAS-mutant lung adenocarcinoma with distinct biology, immune profiles, and therapeutic vulnerabilities.
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Academic Article
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Characterization of twenty-five ovarian tumour cell lines that phenocopy primary tumours.
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Academic Article
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Decoupling of the PI3K Pathway via Mutation Necessitates Combinatorial Treatment in HER2+ Breast Cancer.
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Academic Article
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Comprehensive Genomic Characterization of Long Non-coding RNAs across Human Cancers.
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Academic Article
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Functional Genomic Landscape of Human Breast Cancer Drivers, Vulnerabilities, and Resistance.
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Academic Article
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Inferring causal molecular networks: empirical assessment through a community-based effort.
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Academic Article
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Multilevel Genomics-Based Taxonomy of Renal Cell Carcinoma.
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Academic Article
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Multiplatform-based molecular subtypes of non-small-cell lung cancer.
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Academic Article
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A Pan-Cancer Proteogenomic Atlas of PI3K/AKT/mTOR Pathway Alterations.
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Academic Article
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A Comprehensive Pan-Cancer Molecular Study of Gynecologic and Breast Cancers.
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Academic Article
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Personalized Preclinical Trials in BRAF Inhibitor-Resistant Patient-Derived Xenograft Models Identify Second-Line Combination Therapies.
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Academic Article
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The ErbB2?Ex16 splice variant is a major oncogenic driver in breast cancer that promotes a pro-metastatic tumor microenvironment.
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Academic Article
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Comprehensive Characterization of Molecular Differences in Cancer between Male and Female Patients.
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Academic Article
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AZD5153: A Novel Bivalent BET Bromodomain Inhibitor Highly Active against Hematologic Malignancies.
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Academic Article
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Rab25 acts as an oncogene in luminal B breast cancer and is causally associated with Snail driven EMT.
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Academic Article
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Musashi RNA-binding protein 2 regulates estrogen receptor 1 function in breast cancer.
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Academic Article
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Clinical outcomes based on multigene profiling in metastatic breast cancer patients.
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Academic Article
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Integrative clustering reveals a novel split in the luminal A subtype of breast cancer with impact on outcome.
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Academic Article
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Identifying Abundant Immunotherapy and Other Targets in Solid Tumors: Integrating RNA-seq and Mass Spectrometry Proteomics Data Sets.
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Academic Article
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Stapled peptide inhibitors of RAB25 target context-specific phenotypes in cancer.
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Academic Article
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Unique protein expression signatures of survival time in kidney renal clear cell carcinoma through a pan-cancer screening.
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Academic Article
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The Library of Integrated Network-Based Cellular Signatures NIH Program: System-Level Cataloging of Human Cells Response to Perturbations.
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Academic Article
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Co-targeting BET and MEK as salvage therapy for MAPK and checkpoint inhibitor-resistant melanoma.
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Academic Article
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Autotaxin exacerbates tumor progression by enhancing MEK1 and overriding the function of miR-489-3p.
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Academic Article
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BRD4 amplification facilitates an oncogenic gene expression program in high-grade serous ovarian cancer and confers sensitivity to BET inhibitors.
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Academic Article
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Niraparib activates interferon signaling and potentiates anti-PD-1 antibody efficacy in tumor models.
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Academic Article
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Breast cancer quantitative proteome and proteogenomic landscape.
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Academic Article
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Integrated transcriptomic-genomic tool Texomer profiles cancer tissues.
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Academic Article
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Context Specificity in Causal Signaling Networks Revealed by Phosphoprotein Profiling.
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Academic Article
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COTI-2, A Novel Thiosemicarbazone Derivative, Exhibits Antitumor Activity in HNSCC through p53-dependent and -independent Mechanisms.
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Academic Article
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Comprehensive characterization of circular RNAs in ~?1000 human cancer cell lines.
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Academic Article
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Transcriptional landscape and clinical utility of enhancer RNAs for eRNA-targeted therapy in cancer.
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Academic Article
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Genome-Wide Profiling of Acquired Uniparental Disomy Reveals Prognostic Factors in Head and Neck Squamous Cell Carcinoma.
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Academic Article
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Molecular Analysis of Clinically Defined Subsets of High-Grade Serous Ovarian Cancer.
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Academic Article
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Multiplex digital spatial profiling of proteins and RNA in fixed tissue.
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Academic Article
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mi-IsoNet: systems-scale microRNA landscape reveals rampant isoform-mediated gain of target interaction diversity and signaling specificity.
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Academic Article
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Neural Crest-Like Stem Cell Transcriptome Analysis Identifies LPAR1 in Melanoma Progression and Therapy Resistance.
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